Unstable blood glucose levels in patients undergoing hemodialysis: concept análisis

Glicemia instável no paciente submetido à hemodiálise: análise de conceito

Main Article Content

Larissa de Lima Ferreira
Ana Raquel Cortês Nelson
Laís Vasconcelos Santos
Camila Sayonara Tavares Gomes
Maria Isabel da Conceição Dias Fernandes
Ana Luísa Brandão de Carvalho Lira
Abstract

Objective: to analyze the concept “Unstable Blood Glucose” in the context of patients undergoing hemodialysis. Methods: conceptual analysis, carried out using the method proposed by Walker and Avant and operationalized through a Scoping Review. Data were collected in January 2023, by searching for eligible publications in national and international databases and catalogs of theses and dissertations. Results: the critical attributes identified were: glycemic variation outside the normal range and hemodialysis. The antecedents identified were: Insufficient food intake/Fasting; Inappropriate use of insulin or hypoglycemic agents; Dialysate without glucose replacement; Diabetes Mellitus; and, Advanced age. The consequences were: Hyperglycemia; Hypoglycemia; Increased morbidity; Increase in mortality; Cerebrovascular events; and, Cardiovascular events. A model case and otherwise and empirical references were also constructed. Conclusions and implications for practice: the analysis of the concept “Unstable Glycemia” generated the definition of susceptibility to glycemic variation outside the normal range during and/or after hemodialysis. This knowledge contributes to a broader understanding of the phenomenon and can support the development of interventions that strengthen the prevention of the effects of glycemic variation in this clientele.

Keywords

Downloads

Download data is not yet available.

Article Details

References

Sociedade Brasileira de Nefrologia (SBN). Diálise e hemodiálise: diferenças e aplicação. SBN; 2019 [acesso em 20 jan 2023]. Disponível em: https://www.sbn.org.br/

Elshahat S, Cockwell P, Maxwell AP, Griffin M, O'Brien T, O'Neill C. The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review. PLoS One. 2020 Mar;15(3). DOI: https://doi.org/10.1371/journal.pone.0230512.

Nerbass FB, Lima HN, Thomé FS, Vieira Neto OM, Sesso R, Lugon JR. Brazilian Dialysis Survey 2021. Braz. J. Nephrol. 2022;45(2):192-8. DOI: https://doi.org/10.1590/2175-8239-JBN-2022-0083en

Daugirdas JT, Blake PG, Ing TS. Manual de diálise. 5. ed. São Paulo: Guanabara Koogan; 2019.

Reddenna L, Basha SA, Reddy KSK. Dialysis Treatment: A comprehensive Description. International Journal of Pharmaceutical Sciences Review and Research. 2014 [access in 2023 Jan 20]; 3(1):1-13. Disponível em: https://ijpras.com/storage/models/article/H1PU7jpHW1WMtxyZEGvKW909Wqn54JvD2ouCW01tVZ0KxtbN3B9Z2RR6gVK3/dialysis-treatment-a-comprehensive-description.pdf

Evaristo LS, Cunha AP, Morais CG, Samselski BJL, Esposito EP, Miranda MKV, et al. Complicações durante a sessão de hemodiálise. Av Enferm. 2020; 38(3):316-324. DOI: https://doi.org/10.15446/av.enferm.v38n3.84229

Santos KAS, Souza WB, Silva CS, Alves AA, Fortes GN, Fortes MF, et al. Principais intercorrências durante sessões de hemodiálise em pacientes com comorbidades. Braz. J. Develop. 2021; 7(2):14066-79. DOI: https://doi.org/10.34117/bjdv7n2-162

Lamine F, Chtioui H, Schwotzer N, Pruijm M, Nobre D, Phan O, et al. Défis dans la prise en charge du diabète en hémodialyse chronique. Rev Med Suisse. 2019 [access in 2023 Oct 02];15(653):1132-1139. Available from: https://europepmc.org/article/med/31148425

Padmanabhan A, Velayudham B, Vijaykumar N, Allauddin S. Evaluation of glycemic status during the days of hemodialysis using dialysis solutions with and without glucose. Saudi J Kidney Dis Transpl. 2018; 29(5):1021-7. DOI: https://doi.org/10.4103/1319-2442.243951.

Watha K, DavenportA, Tangvoraphonkchai K. Changes in blood glucose and lactate concentrations with hemodialysis. Artificial Organs. 2022; 46(1):138–145. DOI: https://doi.org/10.1111/aor.14097

Herdman TH, Kamitsuru S. Diagnósticos de enfermagem da NANDA: definições e classificações 2018-2020. Porto Alegre: Artmed; 2018.

Walker L, Avant KC. Conceptanalysis. In: Walker L, Avant KC. Strategies for theory construction in nursing. California: Appleton & Lange; 2011.

Peters MDJ, Godfrey C, Mclnerney P, Mun Z, Tricco AC, Khalil, H. Chapter 11: Scoping Reviews (2020 version). In: Aromataris E, Munn Z. JBI Reviewer’s Manual, JBI; 2020.

Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, et al. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Ann Intern Med. 2018;169(7):467-73. DOI: https://doi.org/10.7326/M18-0850

Hayashi A, Matoba K, Ohata Y, Shimizu N, Suzuki A, Fujii S, et al. Evaluation of the relationship between hemodialysis-related glycemic variability and hormonal profiles in patients with type 2 diabetes on hemodialysis: a pilot study. Ren Replace Ther. 2022; 8(43). DOI: https://doi.org/10.1186/s41100-022-00429-0

Li J, Zhang R, Wu Z, Guo J, Wang Z, Li S, et al. Blood Glucose Fluctuation in Older Adults with Diabetes Mellitus and End-Stage Renal Disease on Maintenance Hemodialysis: An Observational Study. Diabetes Ther. 2022; 13(7):1353-1365. DOI: https://doi.org/10.1007/s13300-022-01274-4.

Khan AHKY, Zakaria NF, Abidin MAZ, Kamaruddin NA. Prevalence of glycemic variability and factors associated with the glycemic arrays among end-stage kidney disease patients on chronic hemodialysis. Medicine (Baltimore). 2021;100(30). DOI: https://doi.org/10.1097/MD.0000000000026729.

Hayashi A, Shimizu N, Suzuki A, Matoba K, Momozono A, Masaki T, et al. Hemodialysis-Related Glycemic Disarray Proven by Continuous Glucose Monitoring; Glycemic Markers and Hypoglycemia. Diabetes Care. 2021; 44(7):1647-1656. DOI: https://doi.org/10.2337/dc21-0269.

Mori K, Emoto M, Abe M, Inaba M. Visualization of Blood Glucose Fluctuations Using Continuous Glucose Monitoring in Patients Undergoing Hemodialysis. J Diabetes Sci Technol. 2019; 13(2):413-414. DOI: https://doi.org/10.1177/1932296818818429.

Akirov A, Diken-Cohen T, Masri-Iragi H, Shimon I. High Glucose Variability Increases Mortality Risk in Hospitalized Patients. J Clin Endocrinol Metab. 2017; 102(7):2230-2241. DOI: https://doi.org/10.1210/jc.2017-00450.

Cryer PE, Axelrod L, Grossman AB, Heller SR, Montori VM, Seaquist ER, et al. Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2009;94(3):709-28. DOI: https://doi.org/10.1210/jc.2008-1410.

Khan AHKY, Zakaria NF, Zainal Abidin MA, Kamaruddin NA. Prevalence of glycemic variability and factors associated with the glycemic arrays among end-stage kidney disease patients on chronic hemodialysis. Medicine (Baltimore). 2021 Jul 30;100(30). DOI: https://doi.org/10.1097/MD.0000000000026729.

Botelho RG, Oliveira CC. Literaturas branca e cinzenta: uma revisão conceitual. Cienc Informação. 2015;44(3):501-13. DOI: https://doi.org/10.18225/ci.inf.v44i3.1804

Woo KT, Choong HL, Wong KS, Tan HB, Chan CM. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int. 2012;81(10):1044-1045. DOI: https://doi.org/10.1038/ki.2012.39.

Federação Internacional de Diabetes (IDF). Diabetes Atlas. 10ª ed. Bruxelas: IDF; 2021[acesso em 02 Jan 2023]. Disponível em: https://www.diabetesatlas.org

Li J, Zhang R, Wu Z, Guo J, Wang Z, Li S, et al. Blood Glucose Fluctuation in Older Adults with Diabetes Mellitus and End-Stage Renal Disease on Maintenance Hemodialysis: An Observational Study. Diabetes Ther. 2022;13(7):1353-1365. DOI: https://doi.org/10.1007/s13300-022-01274-4.

Abe M, Kaizu K, Matsumoto K. Plasma insulin is removed by hemodialysis: evaluation of the relation between plasma insulin and glucose by using a dialysate with or without glucose. Ther Apher Dial. 2007;11(4):280-7. DOI: https://doi.org/10.1111/j.1744-9987.2007.00491.x.

Abe M, Kaizu K, Matsumoto K. Evaluation of the hemodialysis-induced changes in plasma glucose and insulin concentrations in diabetic patients: comparison between the hemodialysis and non-hemodialysis days. Ther Apher Dial. 2007;11(4):288-95. DOI: https://doi.org/10.1111/j.1744-9987.2007.00492.x.

Jamaludin UK, Docherty PD, Geoffrey Chase J, Shaw GM. Impact of Haemodialysis on Insulin Kinetics of Acute Kidney Injury Patients in Critical Care. J Med Biol Eng. 2015;35(1):125-133. DOI: https://doi.org/10.1007/s40846-015-0015-x.

Abe M, Kalantar-Zadeh K. Haemodialysis-induced hypoglycaemia and glycaemic disarrays. Nat Rev Nephrol. 2015 May;11(5):302-13. DOI: https://doi.org/10.1038/nrneph.2015.38.

Castro MCM. Atualização em diálise: complicações agudas em hemodiálise. J Bras Nefrol. 2001 [acesso em 02 Jan 2023]; 23(2):108-13. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/lil-401027

Seaquist ER, Miller ME, Bonds DE, Feinglos M, Goff DC Jr, Peterson K, et al. The impact of frequent and unrecognized hypoglycemia on mortality in the ACCORD study. Diabetes Care. 2012;35(2):409-14. DOI: https://doi.org/10.2337/dc11-0996.

Gomes PM, Foss MC, Foss-Freitas MC. Controle de hiperglicemia intra-hospitalar em pacientes críticos e não-críticos. Medicina (Ribeirão Preto). 2014; 47(2): 194-200. DOI: https://doi.org/10.11606/issn.2176-7262.v47i2p194-200

Drechsler C, Krane V, Ritz E, März W, Wanner C. Glycemic control and cardiovascular events in diabetic hemodialysis patients. Circulation. 2009;120(24):2421-8. DOI: https://doi.org/10.1161/CIRCULATIONAHA.109.857268.

Maruyama N, Abe M. Targets and Therapeutics for Glycemic Control in Diabetes Patients on Hemodialysis. Contrib Nephrol. 2018; 196:37-43. DOI: https://doi.org/10.1159/000485695.

Viana RAPP, Withaker IY, Zanei SSV. Enfermagem em terapia intensiva: práticas e vivências. Porto Alegre: Artmed; 2020.

Gallieni M, Salvo C, Lunati ME, Rossi A, D'Addio F, Pastore I, et al. Continuous glucose monitoring in patients with type 2 diabetes on hemodialysis. Acta Diabetol. 2021;58(8):975-981. DOI: https://doi.org/10.1007/s00592-021-01699-6.

Mian Z, Hermayer KL, Jenkins A. Continuous Glucose Monitoring: Review of an Innovation in Diabetes Management. The American Journal of the medical sciences. 219; 358(5):332-339. DOI: https://doi.org/10.1016/j.amjms.2019.07.003.

Bolinder J, Antuna R, Geelhoed-Duijvestijn P, Kröger J, Weitgasser R. Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non-masked, randomised controlled trial. Lancet. 2016;388(10057):2254-2263. DOI: https://doi.org/10.1016/S0140-6736(16)31535-5.

Haak T, Hanaire H, Ajjan R, Hermanns N, Riveline JP, Rayman G. Flash Glucose-Sensing Technology as a Replacement for Blood Glucose Monitoring for the Management of Insulin-Treated Type 2 Diabetes: a Multicenter, Open-Label Randomized Controlled Trial. Diabetes Ther. 2017;8(1):55-73. DOI: https://doi.org/10.1007/s13300-016-0223-6.

Kidney International. KDIGO 2020 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease. 2020 [access in 2023 Jan 20]; 98(4S): 1–115. Availble from: https://kdigo.org/wp-content/uploads/2021/07/KDIGO-2020-Diabetes-in-CKD-GL.pdf

Mori K, Emoto M, Abe M, Inaba M. Visualization of Blood Glucose Fluctuations Using Continuous Glucose Monitoring in Patients Undergoing Hemodialysis. J Diabetes Sci Technol. 2019; 13(2):413-414. DOI: https://doi.org/10.1177/1932296818818429.

Ricks J, Molnar MZ, Kovesdy CP, Shah A, Nissenson AR, Williams M, et al. Glycemic control and cardiovascular mortality in hemodialysis patients with diabetes: a 6-year cohort study. Diabetes. 2012; 61(3):708–15. DOI: https://doi.org/10.2337/db11-1015.

Bailey TS, Grunberger G, Bode BW, Handelsman Y, Hirsch IB, Jovanovič L, et al. American Association of Clinical Endocrinologiests and American College of Endocrinology 2016 outpatient glucose monitoring consensus statement. Endocrine practice. 2016; 22(2):231-261. DOI: https://doi.org/10.4158/EP151124.CS.

National Institute for Health and Care Excellence: Guidelines [Internet]. London: National Institute for Health and Care Excellence (NICE); 2003 [access in 2023 Feb 05]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK11822/

Leelarathna L, Wilmot EG. Flash forward: a review of flash glucose monitoring. Diabetic Medicine. 2018; 35(4): 472-482. DOI: https://doi.org/10.1111/dme.13584

Khan AHKY, Zakaria NF, Abidin MAZ, Lim CTS, Kamaruddin NA. Glycemic Patterns and Factors Associated with Post-Hemodialysis Hyperglycemia among End-Stage Renal Disease Patients undergoing Maintenance Hemodialysis. J ASEAN Fed Endocr Soc. 2020; 35(1):68-76. DOI: https://doi.org/10.15605/jafes.035.01.12

Viana RAPP, Santos LP, Silveira RC, Siqueira Júnior AG, organizadores. Enfermagem em terapia intensiva: práticas e vivências. Porto Alegre: Artmed; 2020.

Evaristo LS, Oliveira F, Santos MJ, Carvalho PA, Marques C. Complicações durante a sessão de hemodiálise. Av. enferm. 2020;38(3):316-24. Disponível em: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-45002020000300316&lng=en&nrm=iso.

Guedes JBB, Silva KF, Lima GAB, Souza EF, Santos LM. Nursing care in hemodialysis: integrative review. R. pesq.: cuid. fundam. Online. 2021;13(1):653-60. Disponível em: http://seer.unirio.br/index.php/cuidadofundamental/article/view/9402/pdf.

OJS System - Metabiblioteca |