Vibrational Spectroscopy as an Alternative for the Discrimination of Illicit Drugs Seized in the City of Cúcuta
Espectroscopia Vibracional Como Una Alternativa Para La Discriminación De Drogas Ilícitas Incautadas En La Ciudad De Cúcuta
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The infrared spectroscopy with Fourier transform coupled to attenuated total reflectance (ATR-FTIR), is being used for the identification of illicit drugs, being an alternative to the method of Gas Chromatography with flame detector or selective mass detector. Additionally, the technique standardized by forensic laboratories for the analysis of seized drugs does not allow differentiation between the two forms of cocaine (base and hydrochloride) marketed. In this investigation, four hundred (400) samples seized in the city of Cúcuta during the period July 2017 to June 2018 were analyzed by the ATR-FTIR technique, performing SNV (Standard Normal Variate) and second spectrum-derived treatment for the discrimination between cocaine base and cocaine hydrochloride forms, in mixtures with phenacetin, caffeine, lidocaine, levamisole adulteration, as well as the presence of lactose and sodium bicarbonate as diluents. A linear discriminant analysis (LDA) model was implemented in order to differentiate the types of cocaine in more complex matrices or adulterants different from those included in the study. 100% of the samples were correctly discriminated and the methodology was validated in two spectrophotometers that were in different environmental conditions of different references.
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