Regulación neuroendocrina del ciclo estral en la hembra bovina
Regulación neuroendocrina del ciclo estral en la hembra bovina
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El conocimientos actual sobre la fisiología reproductiva ha modificado sustancialmente los conceptos que existían sobre la regulación del ciclo estral, situación que se ha producido básicamente a causa del desarrollo de la biotecnología de la reproducción, principalmente la transferencia de embriones y la fecundación in vitro, las que han exigido de un conocimiento cabal de los procesos de tipo estructural y funcional de los órganos que constituyen el eje hipotálamo-hipófisis-ovario, además se ha profundizado también en los roles protagónicos del útero y el embrión, en todo este complejo proceso. El objetivo de esta revisión es exponer de modo accesible una visión general de la regulación neuroendocrina del ciclo estral, precisando los aspectos que constituyen los núcleos conceptuales de este proceso, de modo tal que pueda comprenderse, con relativa facilidad, las variaciones que frecuentemente se observan en el comportamiento del ciclo de las hembras bovinas.
Palabras Clave: Ciclo estral vaca; foliculogénesis; dinámica folicular; ovocitación.Downloads
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Adams, G.P.; Kot, K.; Smith, C.A. and Ginther, O.J. Selection of a dominant follicle and supression of follicular growth in heifers. Anim. Reprod. Sci. 30: 259-271. 1993.
Adams, G.P.; Matteri, R.L.; Kastelic, J.P.; Ko, J.C.H. and Ginther, O.J. Association between surges of follicle- stimulating hormone and the emergence of follicular waves in heifers. J. Reprod. Fert. 94: 177-188. 1992.
Blanco, A.G.S. y Campo, P.E. Mecanismos neurohormonales del ciclo estral en la vaca. Monografía. La Habana. 1997.
] Campo, E.; Alonso, J.C. y García Libertad. Influencia de la época del año en el comportamiento reproductivo de búfalos. Rev. Salud Animal. 6: 27-29. 1984.
Campo, E.; Rizo, J.M. y García Libertad. Evaluación clínica del puerperio en vacas lecheras. Rev. Salud Animal. 7: 477-484. 1985.
] De la Sota, R.L.; Simmen, F.A.; Diaz, T. and Thatcher, W.W. Insulin-like growth factor system in bovine first-wave dominant and subordinate follicle. Biol. Reprod. 55: 803-812. 1996.
Denis, G. y Gil, A. Aplicaciones prácticas de la ultrasonografía en los programas de transferencia de embriones. Centro de Investigación para la Mejora Animal. La Habana. Cuba. 1997.
Duchens, M. Influence of suprabasal progesterone on preovulatory follicle development in heifers. Doctoral thesis. Swedish University of Agricultural Sciences. Uppsala. Swedish. 1969.
Findlay, J.K. An update on the roles of inhibin, activin and follistatin as local regulators of folliculogenesos. Biol. Reprod. 48: 15-23. 1993.
Flows, J.A.; Desanti, A.; Tilly, K.I.; Javid, R.O.; Kugu, K. and Johanson, A.L. Vasoactive intestinal peptidemediated suppression of apoptosis in the ovary:potential mechanisms of action and evidence of a conserved anti-atretogenic role through evolution.Endocrinology. 136: 4351-4359. 1995.
Fortune, J.E.; Sirois, J. and Quirk, S.M. The growth and differentiation of ovarian follicles during the bovine estrous cycle. Theriogenology. 29: 95-109. 1988.
Fortune, J. E.. Ovarian follicular growth and development in mammals. Biol. Reprod. 50:225. 1994.
Ginther, O.J.; Bergfelt, D.R.; Kulick, L.J. and Kot, K. Pulsatility of systemic FSH and LH concentration during follicular-wave development in cattle. Theriogenology. 50: 507-519. 1998.
Ginther, O.J.; Wiltbank, M.C.; Fricke, P.M.; Gibbons,J.R. and Kot, K. Selection of the dominant follicle in cattle. Biol. Reprod. 55: 1187-1194. 1996.
Holy, L. Biología de la reproducción bovina. Editorial científico técnica. La Habana. Cuba. Pp: 117-123. 1987.
Hunter, M. Characteristics and cause of the inadequate corpus luteum. J. Reprod. Fert. 43: 91-99. 1991.
Jolly, P.D.; Tisdall, D.J.; Heath, D.A.; Lun, S. and McNatty, K.P. Apoptosis of bovine granulosa cells in relation to steroid synthesis, cyclic adenosine 3 ́, 5 ́-monophosphate response to follicle stimulating hormone and luteinizing hormone and follicular atresia. Biol. Reprod. 51: 934-944. 1994.
Karsch, F.J.; Bowen, J.M.; Caraty, A.; Evans, N.P. and Moenter, S.M. Gonadotropin-releasing hormone requirements for ovulation. Biol. Reprod. 56: 303-309. 1997.
Kastelic, J.P.; Ko, J.C.H. and Ginther, O.J. Supression of dominant and subordinate ovarian follicles by a proteinaceous fraction of follicular fluid in heifers. Theriogenology. 34: 499-509. 1990.
Knight, P. G., and C. Glister.. Potential local regulatory functions of inhibins, activins and follistatin in the ovary. Reproduction 121:503. 2001.
Knopf, L.; Kastelic, J.P.; Schallember, E. and Ginther, O.J. Ovarian follicular dymanics in heifers. Test of two wave hypothesis by ultrasonically monitoring individual follicles. Domest. Anim. Endocrin. 6: 111-119. 1989.
Ko, J.C.H.; Kastelic, J.P.; del Campo, M. R. and Ginther, O.J. Effects of a dominant follicle on ovarian follicular dynamics during the oestrous cycle in heifers. J. Reprod. Fert. 91: 511-519. 1991.
Kojima, F. N., and D. J. Patterson. 2003. Guide to Estrus Synchronization of Beef Cattle. University of Missouri, Columbia, MO.
Lussier, J.G.; Matton, P. and Dufour, J.J. Growth rates of follicles in the bovine ovary. J. Reprod. Fertil. 81: 301-307. 1987.
Monget, P. and Monniaux, D. Growth factors and the control of folliculogenesis. J. Reprod. Fert. Suppl. 49: 321-333. 1995.
Monget P, Fabre S, Mulsant P, Lecerf F, Elsen JM, Mazerbourg S, Pisselet C, Monniaux D. Regulation of ovarian folliculogenesis by IGF and BMP system in domestic animals. Domest Anim Endocrinol.;23:139. 2002.
Monniaux, D.; Monget, P.; Besnard, N.; Huet, C. and Pisselet, C. Growth factor and antral follicular development in domestic rumiants. Theriogenology. 47:3-12. 1997.
Monniaux, F; Huet, C.; Besnard, N.; Clément, F.; Bosc, H.; Pisselet, C.; Monget, P. and Mariana, J.C. Follicular growth and ovarian dynamics in mammals. J. Reprod. Fert. 112: 25-31. 1997.
Murphy, B.D. y Pescador, N. Control de la foliculogénesis bovina por factores endocrinos y paracrinos. VII Curso Internacional de Reproducción Bovina. Centro Médico Nacional. Siglo XXI. D.F. México. 1997.
Newton, G.R.; Martinod, S.; Hansen, P.J.; Thatcher, W.W.; Siegenthaler, B.; Gerber, C. and Voirol, M.J. Effect of bovine interferon on acute changes in body temperature and serum progesterone concentration in heifers. J. Dairy Sci. 73: 3439-3448. 1990.
Niswender, G.D.; Juengel, J.L. and McGuire, W.J. The strous cycle and early pregnancy. Biol. Reprod. 50: 239-245. 1994.
O ́shea, T.; Hillard, M.A.; Anderson, S.T.; Bindon, B.M.; Findlay, J.K.; Tsonis, C.G. and Wilkens, J.F. Inhibin immunization for increasing ovulatory rate and superovulation. Theriogenology. 41: 3-17. 1994.
Oktay, K.; Schencken, R.S. and Nelson, J.F. Proliferating cell nuclear antigen marks the initiation of follicular growth in the rat. Biol. Reprod. 53: 295-301. 1995.
Peluso, J.J.; Pappalardo, A. and Trolice, M.P. N- cadherin-mediated cell contact inhibits granulosa cell apoptosis in a progesterone dependent manner.Endocrinology. 137: 1196-1203. 1995.
Rajakoski, E. The ovarian follicular system in sexually mature heifers with special reference to seasonal, ciclical and left-right variations. Acta. Endocrinol. 34: 1-6. 1960.
Rivera, C. Regulación neuroendocrina de la función ovárica. En: Transferencia de embriones y biotecnología de la reproducción. Ed. Hemisferio Sur. Argentina. 1993.Roberts, R. and Smith, M. Luteal function after intrauterine infusion of recombinante bovine interferon.J. Reprod. Fert. 94: 319-325. 1992.
Roche, J.f. and Boland, M.P. Turnover of dominant follicles in cattle of different reproductive states. Theriogenology. 35: 81-90. 1991.
Roche, J.F. Control and regulation of folliculogenesis. A symposium in perspective. Rev. Reprod. 1: 19-27.1996.
Savio, J.D.; Keenal, L.; Boland, M.P. and Roche, J.F.Ovarian follicular development during the oestrous cycle in heifers. J. Reprod. Fert. 77: 124-130. 1987.
Savio, J.D.; Keenan, L.; Bonald, M.P. and Roche, J.F. Patterns of growth of dominant folicles during the oestrous cycle of heifers. J. Reprod. Fert. 83: 663-671. 1988.
Savio, J.D.; Thatcher, W.W.; Badinga, L.; de la Sota,R.L. and Wolfenson, D. Regulation of dominant follicle turnover during the oestrous cycle in cows. J. Reprod. Fertility. 97: 197-203. 1993.
Silvia, W. and Taylor, M. Relationship between uterine secretion of prostaglandinF2 alpha induced by oxytocin and endogenous concentrations of E2 y P4 and three stage of the bovine estrous cycle. J. Anim. Sci. 67: 2347-2353. 1989.
Silvia, W.; Lewis, G. and Wilson, J. Hormonal regulation of uterine secretion of prostaglandine F2 alpha. Biol. Reprod. 45: 655-663. 1991.
Sirois, J. and Fortune, J.E. Ovarian follicular dynamics during the estrous cycle in heifers monitored by realtime ultrasonography. Biol. Reprod. 39: 308-317. 1988.
L.J Spicer, CC Chase Jr, L M Rutter. Relationship between serum insulin-like growth factor-I and genotype during the postpartum interval in beef cows. Journal of Animal Science. 80:716. 2002.
Sugino, K.; Norosawa, N.; Nakamura, T.; Takio, K.; Shimasaki, S.; Ling, N.; Titani, K. and Sugino, H.Molecular heterogeneity of follistatin an activin-binding protein. J. Biol. Chem. 286: 15579-15587. 1993.
Sunderland, S.J.; Growe, M.A.; Boland, M.P.; Roche, J.F. and Ireland, J.J. Selection, dominance and atresia of follicles during the oestrous cycle of heifers. J. Reprod. Fert. 101: 547-555. 1994.
Tilly, J.L.; Kowalski, K.I.; Johnson, A.L. and Hsuch, A.J.W. Involvement of apoptosis in ovarian follicular atresia and postovulatory regresion. Endocrinology. 129: 2799-2801. 1991.
Wiltbank, M.C.; Shiao, T.F. and Bergfelt, D.R.Prostaglandin F2μ receptors in the early bovine corpus luteum. Biol. Reprod. 52: 74-80. 1995.
Zarco, L. Infertilidad debida a asincronia materno- embrionaria en rumiantes. VI Curso Internacional de Reproducción Bovina. Centro Médico Nacional. Siglo XXI. D.F. México. 1995.
Zollers, W.G.; Garverick, H.A.; Smith, M.F.; Moffatt, R.J.; Salfen, B.E. and Youngquist, R.S. Concentration of progesterone and oxitocin receptors in endometrium of postpartum cows expected to have a short or normal oestrus cycle. J. Reprod. Fertility. 97: 329-337. 1993.